|
KMID : 0388419920020010121
|
|
Konkuk Journal of Medical Sciences
1992 Volume.2 No. 1 p.121 ~ p.128
|
|
|
The Effect of Intravenous Urokinase Therapy in Acute Myocardial Infarction
|
|
|
|
|
Abstract
|
|
|
Coronary thrombosis plays a key role in the development of acute transmural myocardial infarction. The early thrombolytic procedure can restore the patency of infarct related artery and improve myocardial performance. We reviewed the records of
the
17
patients who were admitted to Minjoong hospital from Sep. 1987 to Dec. 1991 under the diagnosis of acute transmural myocardial infarction. The intravenous coronary thrombolysis with urokinase(IV UK) was performed in 9 patients(Group 1) and the
other 8
patients were treated by conventional methods(Group 2).
The age, sex distribution, serum cholesterol, site of myocardial infarction and peak, CK level were not significantly different between two group. The interval between symptom onset to peak CK level was significantly decreased in group
1(15.1±5.2
vs
29.8±12.2).
The result of coronary thrombolysis was evaluated by non invasive methods and was effective in 5 cases of group 1. The complication of IV UK was minimal in this study. In conclusion, the intravenous coronary thrombolysis with urokinase was safe
and
effective method in the treatment of acute myocardial infarction.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|